For context, during diet-only weight loss without medication, lean mass loss typically accounts for about 20 to 30% of total weight lost
What if my previous semaglutide prescription expired during the break
In cases where resistance exercise is excluded from the weight loss regimen, weight loss frequently results in a loss of muscle mass
Reference: Association between GLP-1 receptor agonist use and worsening mental illness in people with depression and anxiety in Sweden: a national cohort study by Heidi Taipale, Mark Taylor, Markku Lhteenvuo, Ellenor Mittendorfer-Rutz, Antti Tanskanen and Jari Tiihonen, April 2026, The Lancet Psychiatry
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SGLT-2 inhibitors and thiazolidinediones may also be used concurrently, though patients should be monitored for any unexpected interactions or adverse effects